I'm attempting to set custom computing preferences (https://scienceunited.org/prefs.php?subset=global). I click the green Edit button, I make changes, then click the green Update button. It claims it updates, and that my client will get the changes the next time it connects. But then, I log out and log back in and all the settings are reset!

Same problem. Computer preferences applied but reset each time you open edit page.

Reporting same issue, though it appears to hold the updated settings for at least a few minutes. Eventually, I check again, and all has been reset to default.

Same issue with me. I decided to alter my preferences directly in BOINC and that works for me.

Same issue here:
The settings are always saved and can be pulled by the client, but the next time you open the custom settings, they won't be read by the webinterface.
Insted default settings will be loaded.
When you don't save the default settings, they will stay as you saved them the last time.
I assume that this happens because there is an issue in the code of the website which can't access the user's settings and instead loads the default settings?